The C1QL2 Polyclonal Antibody (PACO00486) is a valuable tool for researchers studying C1QL2, a protein involved in synaptic pruning and regulation of neuronal connectivity. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot assays. By specifically binding to the C1QL2 protein, this antibody allows for accurate detection and analysis in various cell types, making it ideal for studies in neuroscience and neurodegenerative diseases.C1QL2 plays a crucial role in the process of synaptic pruning, which is essential for refining neural circuitry during brain development and plasticity.
Dysregulation of this process has been implicated in various neurological disorders, making C1QL2 a promising target for research into conditions such as autism, schizophrenia, and Alzheimer's disease. Understanding the function of C1QL2 can provide valuable insights into the mechanisms underlying these disorders and aid in the development of novel therapeutic strategies.
Antibody Name:
C1QL2 Antibody
Antibody SKU:
PACO00486
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human C1qL2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
C1QL2; Complement C1q-like protein 2
UniProt Protein Function:
C1QL2: May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 2q14.2Cellular Component: collagen; extracellular regionMolecular Function: identical protein bindingBiological Process: protein oligomerization
