The C1QC Polyclonal Antibody (CAB9227) is a powerful tool for researchers studying the C1QC protein, a key component of the C1q complex involved in the classical pathway of the complement system. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.C1QC is essential for the recognition and elimination of pathogens, immune complexes, and damaged cells by the immune system. Dysregulation of the complement system, including C1QC, has been implicated in various diseases, such as autoimmune disorders, infectious diseases, and neurodegenerative conditions.
By targeting C1QC, researchers can gain insights into the mechanisms underlying these diseases and potentially develop novel therapies for targeting the complement system. The C1QC Polyclonal Antibody is a valuable tool for investigating C1QC expression and function in different experimental settings, offering new opportunities for advancements in immunology and disease research.
Product Name:
C1QC Rabbit Polyclonal Antibody
SKU:
CAB9227
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human C1QC (NP_001107573.1).
This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
Purification Method:
Affinity purification
Gene ID:
714
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from human serum, using C1QC Rabbit pAb (CAB9227) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
