The C1qb Polyclonal Antibody (CAB5339) is a valuable tool for researchers studying the immune system and its role in disease. This antibody, raised in rabbits, is highly specific for the C1qb protein and is validated for use in a variety of applications, including Western blotting. By targeting C1qb, a key component of the complement system involved in immune response and inflammation, this antibody enables researchers to detect and analyze C1qb levels in various cell types.
C1qb has been implicated in a range of diseases, including autoimmune disorders, infectious diseases, and neurodegenerative disorders. Understanding the role of C1qb in the immune system is essential for developing targeted therapies and diagnostics for these conditions. The C1qb Polyclonal Antibody is a reliable tool for researchers seeking to expand their knowledge of immune regulation and its implications for human health.
Product Name:
C1QB Rabbit Polyclonal Antibody
SKU:
CAB5339
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 104-253 of human C1QB (NP_000482.3).
This gene encodes the B-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
Purification Method:
Affinity purification
Gene ID:
713
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and 293T cells transfected with C1QB using C1QB Rabbit pAb(CAB5339) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime: 5s.
