The C1qa Polyclonal Antibody (CAB24519) is a valuable tool for researchers studying the C1qa protein, a vital component of the complement system involved in immune response and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. It specifically binds to the C1qa protein, facilitating its detection and analysis in various cell types.The C1qa protein is essential for the activation of the classical complement pathway, a key part of the innate immune response.
Dysregulation of the complement system, including C1qa, has been linked to a range of diseases, making it a promising target for therapeutic interventions. By elucidating the function and regulation of C1qa, researchers can better understand its role in diseases such as autoimmune disorders, inflammatory conditions, and infectious diseases.Overall, the C1qa Polyclonal Antibody is a reliable tool for investigating the role of C1qa in immune response and inflammation, providing valuable insights for the development of new therapeutic strategies.
Product Name:
C1qa Polyclonal Antibody
SKU:
CAB24519
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-245 of mouse C1qa (NP_031598.2).
Involved in several processes, including complement-mediated synapse pruning; microglial cell activation; and nervous system development. Acts upstream of or within complement activation, classical pathway. Located in postsynapse. Is expressed in brain; foot; genitourinary system; and pancreas. Used to study epilepsy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in glomerulonephritis. Orthologous to human C1QA (complement C1q A chain).
Purification Method:
Affinity purification
Gene ID:
12259
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using C1qa Rabbit pAb (CAB24519) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
