The C1GALT1C1 Polyclonal Antibody (CAB7590) is a powerful tool for researchers studying C1GALT1C1, a key enzyme involved in glycosylation processes. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting C1GALT1C1 in human samples, making it an ideal choice for Western blot applications.C1GALT1C1 plays a crucial role in the glycosylation of proteins, which is essential for proper protein function and cell signaling. Dysregulation of glycosylation processes, including alterations in C1GALT1C1 activity, has been implicated in various diseases, such as cancer and congenital disorders.
By using the C1GALT1C1 Polyclonal Antibody, researchers can gain valuable insights into the role of C1GALT1C1 in disease pathogenesis and potential therapeutic strategies targeting glycosylation pathways.Overall, the C1GALT1C1 Polyclonal Antibody is a valuable tool for researchers looking to unravel the complex mechanisms of glycosylation and its impact on human health. Its high specificity and reliability make it a reliable choice for studying C1GALT1C1 in both basic science and clinical research settings.
Product Name:
C1GALT1C1 Rabbit Polyclonal Antibody
SKU:
CAB7590
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human C1GALT1C1 (NP_689905.1).
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Purification Method:
Affinity purification
Gene ID:
29071
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using C1GALT1C1 antibody (CAB7590) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
