The C1GALT1 Polyclonal Antibody (CAB12865) is a valuable tool for researchers studying C1GALT1, an enzyme involved in protein glycosylation and cell signaling processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the C1GALT1 protein, this antibody allows for the detection and analysis of C1GALT1 levels in various cell types, making it ideal for research in glycobiology and cancer biology.C1GALT1 plays a crucial role in modifying proteins with specific sugar molecules, which can impact various cellular functions such as cell adhesion, migration, and signaling.
Dysregulation of C1GALT1 expression has been linked to cancer progression, making it a potential target for cancer therapy development. By studying the expression and function of C1GALT1, researchers can gain insights into its role in disease pathology and potentially identify new therapeutic strategies for cancer treatment.
Product Name:
C1GALT1 Rabbit Polyclonal Antibody
SKU:
CAB12865
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 194-363 of human C1GALT1 (NP_064541.1).
The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.
Purification Method:
Affinity purification
Gene ID:
56913
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using C1GALT1 Rabbit pAb (CAB12865) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
