The C19orf12 Polyclonal Antibody (PACO53966) is a valuable tool for researchers studying the C19orf12 gene, which has been implicated in various diseases and cellular processes. This antibody, produced in rabbits, is highly specific and sensitive for detecting C19orf12 protein in human samples, making it suitable for a range of applications including Western blotting.C19orf12, also known as chromosome 19 open reading frame 12, has been linked to neurodegenerative disorders and mitochondrial dysfunction.
By targeting the C19orf12 protein, researchers can explore its role in these diseases, as well as its potential as a therapeutic target. This antibody enables precise detection and analysis of C19orf12 expression in different cell types, providing valuable insights into its function and potential clinical relevance.
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO53966 at dilution of 1:100.
Immunofluorescence staining of MCF-7 cells with PACO53966 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO53966 at dilution of 1:100.
Synonyms:
Protein C19orf12, C19orf12
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a small transmembrane protein. Mutations in this gene are a cause of neurodegeneration with brain iron accumulation-4 (NBIA4), but the specific function of the encoded protein is unknown. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
