The C14orf166 Polyclonal Antibody (CAB3436) is a specialized research tool designed for studying the C14orf166 protein, a key player in cellular functions and pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human biological samples, enabling accurate detection and analysis in various experimental settings.C14orf166, also known as Chromosome 14 Open Reading Frame 166, is a poorly characterized protein with potential implications in several biological processes, including signal transduction and gene regulation. By targeting C14orf166, researchers can gain valuable insights into its role in cell biology, offering new avenues for investigating diseases and therapeutic interventions.
Validated for use in Western blot applications, the C14orf166 Polyclonal Antibody (CAB3436) provides researchers with a powerful tool for exploring the functions and interactions of C14orf166 in different cell types and experimental conditions. Its utility in molecular biology, biochemistry, and cell biology studies makes it an essential component for laboratories focused on uncovering the mysteries of cellular function and disease mechanisms.
Product Name:
C14orf166 Rabbit Polyclonal Antibody
SKU:
CAB3436
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human C14orf166 (NP_057123.1).
Cytoplasm, Nucleus, centrosome, cytoskeleton, cytosol, microtubule organizing center, perinuclear region.
Calculated MW:
28kDa
Observed MW:
25kDa/28kDa
Enables RNA binding activity; RNA polymerase II complex binding activity; and identical protein binding activity. Involved in negative regulation of protein kinase activity; positive regulation of transcription by RNA polymerase II; and tRNA splicing, via endonucleolytic cleavage and ligation. Located in microtubule cytoskeleton; nucleoplasm; and perinuclear region of cytoplasm. Part of tRNA-splicing ligase complex.
Purification Method:
Affinity purification
Gene ID:
51637
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using C14orf166 antibody (CAB3436) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
