The C10orf54 Polyclonal Antibody (CAB10419) is a valuable tool for research involving the C10orf54 protein, a cell surface molecule with key functions in immune regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the C10orf54 protein, this antibody enables precise detection and analysis in a variety of cell types, making it particularly useful for studies in immunology and cancer research.C10orf54 plays a crucial role in immune response modulation, making it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Its involvement in immune homeostasis highlights its potential as a therapeutic target for the development of treatments that aim to either enhance or suppress immune function in these pathological contexts. By understanding the functions of C10orf54, researchers can pave the way for innovative therapies that could have a significant impact on disease management and treatment outcomes.
Product Name:
VISTA Rabbit Polyclonal Antibody
SKU:
CAB10419
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-194 of human VISTA (NP_071436.1).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
34kDa
Observed MW:
37kDa
Enables endopeptidase activator activity; enzyme binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of cytokine production; positive regulation of macromolecule metabolic process; and regulation of T cell activation. Located in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
64115
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VISTA antibody (CAB10419) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
