C10orf2 Rabbit Polyclonal Antibody (CAB5303)
- SKU:
- CAB5303
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | C10orf2 Rabbit Polyclonal Antibody |
SKU: | CAB5303 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 135-335 of human C10orf2 (NP_068602.2). |
Sequence: | GARE GFLL SKAP EFED SEEV RRIW NRAI PLWE LPDQ EEVQ LADT MFGL TKVT DDTL KRFS VRYL RPAR SLVF PWFS PGGS GLRG LKLL EAKC QGDG VSYE ETTI PRPS AYHN LFGL PLIS RRDA EVVL TSRE LDSL ALNQ STGL PTLT LPRG TTCL PPAL LPYL EQFR RIVF WLGD DLRS WEAA KLFA RKLN PKRC FLVR P |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | PEO; PEO1; SCA8; ATXN8; IOSCA; PEOA3; SANDO; TWINL; MTDPS7; PRLTS5; C10orf2 |
Positive Sample: | A-549,A-431,Mouse heart,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix, mitochondrion nucleoid. |
Calculated MW: | 77kDa |
Observed MW: | 77kDa |
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 56652 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |