The C10orf2 Polyclonal Antibody (CAB13433) is a valuable tool for researchers studying the C10orf2 protein, also known as chromosome 10 open reading frame 2. This antibody, raised in rabbits, specifically targets C10orf2 and is highly reactive with human samples. It has been validated for use in Western blot applications, allowing for the detection and analysis of C10orf2 in various cell types.C10orf2 is a poorly characterized protein with potential implications in various cellular processes, including cell growth, proliferation, and differentiation.
Research on C10orf2 is essential for understanding its role in normal cellular function and its potential involvement in diseases such as cancer. The C10orf2 Polyclonal Antibody provides a reliable means of studying this protein, making it an ideal choice for immunology and cancer research studies.
Product Name:
C10orf2 Rabbit Polyclonal Antibody
SKU:
CAB13433
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 585-684 of human C10orf2 (NP_068602.2).
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method:
Affinity purification
Gene ID:
56652
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using C10orf2 Rabbit pAb (CAB13433) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
