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C-Myc [PAT19B4AT] (CPAB0648)

SKU:
CPAB0648
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
€149
Frequently bought together:

Description

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C-Myc [PAT19B4AT] (CPAB0648)

The c-Myc (410-419aa) Polyclonal Antibody (CPAB0648) is a valuable tool for researchers studying the c-Myc protein, a key regulator of cell growth, proliferation, and metabolism. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for a variety of applications, including Western blot analysis.c-Myc is a transcription factor that plays a crucial role in various cellular processes, including cell cycle progression, apoptosis, and differentiation. Dysregulation of c-Myc expression is frequently associated with cancer development and progression, making it an important target for cancer research.

Researchers interested in studying the function and regulation of c-Myc can rely on the c-Myc (410-419aa) Polyclonal Antibody to detect and analyze the protein in different cell types and experimental conditions. By gaining insights into the role of c-Myc in normal and disease states, researchers can develop novel therapeutic strategies for targeting c-Myc-driven cancers and other diseases.

Product Name:C-Myc (410-419aa) Antibody
Product Sku:CPAB0648
Size:5μg
Host Species:Mouse
Immunogen:Anti-human C-Myc mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human C-Myc protein 41-419 amino acids purified from Ecoli.
Clone:PAT19B4AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:C-Myc antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Synonyms:MYC, CMYC, C-MYS, V-MYC, P64.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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