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c-Jun Transcription Factor Activity Assay

SKU:
TFAB00076
Product Type:
ELISA Kit
ELISA Type:
Transcription Factor Assay
Analytes:
c-Jun
Reactivity:
Human
Mouse
Rat
$719
Frequently bought together:

Description

system_update_altDatasheet

c-Jun Transcription Factor Activity Assay

The c-Jun Transcription Factor Activity Assay Kit is a powerful tool for studying the activity of the c-Jun transcription factor in various biological samples. This assay kit provides researchers with a highly sensitive and specific method for detecting c-Jun activity in cell lysates, tissue homogenates, and other sample types.The c-Jun transcription factor is a key regulator of gene expression, playing a critical role in cell proliferation, differentiation, and apoptosis. Dysregulation of c-Jun activity has been linked to numerous diseases, including cancer, inflammatory disorders, and neurodegenerative conditions. By accurately measuring c-Jun activity, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and explore potential therapeutic targets.

With its easy-to-use protocol and reliable results, the c-Jun Transcription Factor Activity Assay Kit is an essential tool for researchers studying transcription factor signaling pathways and exploring the role of c-Jun in various biological processes. Whether investigating basic science questions or working towards drug discovery efforts, this kit offers a reliable and efficient method for measuring c-Jun activity in a variety of sample types.

Product Name:c-Jun Transcription Factor Activity Assay
Product Code:TFAB00076
Target:c-Jun
Synonyms:Activator protein 1, AP1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog, p39
Reactivity:Human, Mouse, Rat
Sample Types:Nuclear or cell lysates

The Assay Genie c-Jun transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates

Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.

Assay Time:4.5 hours
Detection Method:Colorimetric 450 nm
Size:12 x 8-Well Microstrips
Storage:4°C for 6 months
UniProt Protein Function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
NCBI Summary:This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq, Jul 2008]
UniProt Code:P05412
NCBI GenInfo Identifier:135298
NCBI Gene ID:3725
NCBI Accession:P05412.2
UniProt Secondary Accession:P05412,Q6FHM7, Q96G93,
UniProt Related Accession:P05412
Molecular Weight:
NCBI Full Name:Transcription factor AP-1
NCBI Synonym Full Names:jun proto-oncogene
NCBI Official Symbol:JUN  
NCBI Official Synonym Symbols:AP1; AP-1; c-Jun  
NCBI Protein Information:transcription factor AP-1
UniProt Protein Name:Transcription factor AP-1
UniProt Synonym Protein Names:Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39
Protein Family:C-Jun-amino-terminal kinase-interacting protein
UniProt Gene Name:JUN  
UniProt Entry Name:JUN_HUMAN
AntibodiesELISA Kits
Anti-c-Jun Antibody (CAB0246)Human C-jun (V-Jun Sarcoma Virus 17 Oncogene Homolog) ELISA Kit (HUES01888)
Anti-c-Jun Antibody (CAB11378)c-Jun (Phospho-Ser63) Colorimetric Cell-Based ELISA Kit
Anti-JUN Antibody (CAB16905)c-Jun (Phospho-Ser243) Colorimetric Cell-Based ELISA Kit
Anti-Phospho-Jun-S73 Antibody (CABP0047)c-Jun (Phospho-Thr239) Colorimetric Cell-Based ELISA Kit
Anti-Phospho-Jun-S63 Antibody (CABP0048)c-Jun (Phospho-Thr91) Colorimetric Cell-Based ELISA Kit

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