The BZLF2 Antibody (PAC058096) is a high-quality polyclonal antibody designed for research involving the BZLF2 protein, a critical transcription factor involved in the lytic cycle of the Epstein-Barr virus. This antibody, raised in rabbits, offers high reactivity with human samples and is validated for use in various applications including Western blot and immunofluorescence.The BZLF2 protein plays a crucial role in the reactivation of the Epstein-Barr virus from latency, leading to viral replication and the production of infectious viral particles. Understanding the function and regulation of BZLF2 is key to unraveling the molecular mechanisms underlying viral reactivation and pathogenesis. This antibody binds specifically to the BZLF2 protein, enabling accurate detection and analysis in different cell types, making it an essential tool for research in virology and infectious diseases.
Research on the BZLF2 protein is important for developing targeted therapies against Epstein-Barr virus-associated diseases, including certain types of cancers like Burkitt's lymphoma and nasopharyngeal carcinoma. By investigating the role of BZLF2 in viral reactivation and pathogenesis, scientists can uncover novel strategies for combating viral infections and related malignancies. Get your hands on the BZLF2 Antibody (PAC058096) today and advance your research in virology and viral pathogenesis.
Antibody Name:
BZLF2 Antibody (PACO58096)
Antibody SKU:
PACO58096
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Epstein-Barr virus
Immunogen:
Recombinant Epstein-Barr virus Glycoprotein 42 protein (34-223AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: BZLF2 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa.
Background:
Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells. Additionally, hampers T-cell recognition via HLA class II molecules through steric hindrance of T-cell receptor-class II-peptide interaction.
Plays a role in virion attachment to host B-lymphocytes, through binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells. Additionally, hampers T-cell recognition via HLA class II molecules through steric hindrance of T-cell receptor-class II-peptide interaction.
