The BUB3 Rabbit Monoclonal Antibody (CAB8831) is a specialized tool for researchers studying the BUB3 protein, a key player in the regulation of the cell cycle and chromosome segregation. This antibody is produced in rabbits and has high specificity for human samples, making it a valuable asset for Western blot applications. By binding to the BUB3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.The BUB3 protein is essential for the proper functioning of the mitotic spindle checkpoint, ensuring accurate chromosome segregation during cell division.
Dysregulation of BUB3 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. By elucidating the role of BUB3 in these pathological processes, researchers can gain valuable insights into the mechanisms underlying disease progression and potentially identify novel therapeutic targets for the treatment of cancer and other disorders.
Product Name:
BUB3 Rabbit Monoclonal Antibody
SKU:
CAB8831
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BUB3 (O43684).
This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method:
Affinity purification
Gene ID:
9184
Clone Number:
ARC1318
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using BUB3 Rabbit mAb (CAB8831) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
