BUB1B Rabbit Polyclonal Antibody (CAB1775)
- SKU:
- CAB1775
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | BUB1B Rabbit Polyclonal Antibody |
SKU: | CAB1775 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human BUB1B (NP_001202.4). |
Sequence: | MAAV KKEG GALS EAMS LEGD EWEL SKEN VQPL RQGR IMST LQGA LAQE SACN NTLQ QQKR AFEY EIRF YTGN DPLD VWDR YISW TEQN YPQG GKES NMST LLER AVEA LQGE KRYY SDPR FLNL WLKL GRLC NEPL DMYS YLHN QGIG VSLA QFYI SWAE EYEA RENF RKAD AIFQ EGIQ QKAE PLER LQSQ HRQF QARV SRQT LLAL EKEE EEEV FESS VPQR STLA ELKS KGKK TARA PIIR VGGA LKAP SQNR GLQN |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MVA1; SSK1; BUBR1; Bub1A; MAD3L; hBUBR1; BUB1beta; BUB1B |
Positive Sample: | U-251MG,HeLa,Jurkat,HT-29,A-549,COS-7,MCF7,DU145 |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Cytoplasm, Nucleus, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center. |
Calculated MW: | 120kDa |
Observed MW: | 55kDa/120kDa |
This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.
Purification Method: | Affinity purification |
Gene ID: | 701 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |