BTNL2 Rabbit Polyclonal Antibody (CAB7120)
- SKU:
- CAB7120
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | BTNL2 Rabbit Polyclonal Antibody |
SKU: | CAB7120 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 246-455 of human BTNL2 (NP_062548.1). |
Sequence: | LKVN GPSQ PILV RVGE DIQL TCYL SPKA NAQS MEVR WDRS HRYP AVHV YMDG DHVA GEQM AEYR GRTV LVSD AIDE GRLT LQIL SARP SDDG QYRC LFEK DDVY QEAS LDLK VVSL GSSP LITV EGQE DGEM QPMC SSDG WFPQ PHVP WRDM EGKT IPSS SQAL TQGS HGLF HVQT LLRV TNIS AVDV TCSI SIPF LGEE KIAT FSLS GW |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:100 - 1:500 |
Synonyms: | SS2; BTN7; BTL-II; HSBLMHC1; BTNL2 |
Positive Sample: | 293T transfected with BTNL2 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type II membrane protein. |
Calculated MW: | 50kDa |
Observed MW: | 65kDa |
This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.
Purification Method: | Affinity purification |
Gene ID: | 56244 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |