The BTN2A1 Polyclonal Antibody (CAB10418) is a valuable tool for researchers working with BTN2A1, a cell surface molecule involved in immune regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the BTN2A1 protein, this antibody enables the detection and analysis of BTN2A1 in various types of cells, making it an ideal choice for studies in immunology and cancer research.
BTN2A1, a member of the butyrophilin family, plays a crucial role in modulating immune responses and has been implicated in the regulation of T cell activation and proliferation. Its involvement in immune regulation highlights its potential as a target for research into autoimmune disorders, cancer, and inflammatory conditions. Understanding the function of BTN2A1 is essential for the development of therapies that can manipulate immune responses in the context of these diseases.
Product Name:
BTN2A1 Rabbit Polyclonal Antibody
SKU:
CAB10418
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTN2A1 (NP_510961.1).
This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
11120
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of RD cells, using BTN2A1 antibody (CAB10418) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
