The BTLA Polyclonal Antibody (CAB8377) is a valuable tool for researchers studying BTLA, a cell surface receptor involved in immune regulation and tolerance. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blotting applications. By binding to the BTLA protein, this antibody allows for the detection and analysis of BTLA expression in various cell types, making it ideal for investigations in immunology and cancer research.BTLA, or B and T lymphocyte attenuator, is a crucial regulator of immune responses, playing a role in maintaining immune balance and preventing excessive inflammation.
Understanding the function of BTLA is essential for unraveling its potential as a therapeutic target in diseases such as cancer, autoimmune disorders, and inflammatory conditions. By utilizing the BTLA Polyclonal Antibody, researchers can gain insights into the mechanisms by which BTLA modulates immune function, paving the way for the development of novel treatment approaches.
Product Name:
BTLA Rabbit Polyclonal Antibody
SKU:
CAB8377
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-241 of human BTLA (NP_001078826.1).
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
Purification Method:
Affinity purification
Gene ID:
151888
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BTLA antibody (CAB8377) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
