The BTLA Polyclonal Antibody (CAB13449) is a valuable tool for researchers studying B and T lymphocyte attenuator (BTLA), an immune checkpoint receptor that plays a key role in regulating immune responses. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it a reliable choice for Western blot applications. By binding to the BTLA protein, this antibody enables researchers to detect and analyze BTLA expression in various cell types, making it ideal for studies in immunology and cancer research.
BTLA is known for its ability to inhibit immune responses, making it a potential target for developing therapies for autoimmune disorders, chronic inflammation, and cancer. By understanding the function of BTLA, researchers can gain valuable insights into immune regulation and potentially discover new treatment approaches for a range of diseases. The BTLA Polyclonal Antibody is a valuable tool for investigating the role of BTLA in immune modulation and developing targeted therapies.
Product Name:
BTLA Rabbit Polyclonal Antibody
SKU:
CAB13449
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 31-241 of human BTLA (NP_001078826.1).
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis.
Purification Method:
Affinity purification
Gene ID:
151888
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using BTLA antibody (CAB13449) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
