BTK Rabbit Monoclonal Antibody (CAB19002)
- SKU:
- CAB19002
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | BTK Rabbit Monoclonal Antibody |
SKU: | CAB19002 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 560-659 of human BTK (Q06187). |
Sequence: | PVRW SPPE VLMY SKFS SKSD IWAF GVLM WEIY SLGK MPYE RFTN SETA EHIA QGLR LYRP HLAS EKVY TIMY SCWH EKAD ERPT FKIL LSNI LDVM DEES |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AT; ATK; BPK; XLA; IMD1; AGMX1; IGHD3; PSCTK1; BTK |
Positive Sample: | Raji,K-562 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein. |
Calculated MW: | 76kDa |
Observed MW: | 76kDa |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 695 |
Clone Number: | ARC0485 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |