The BTK Rabbit Monoclonal Antibody (CAB19002) is a valuable tool for researchers studying the role of Bruton's tyrosine kinase (BTK) in immune cell signaling and autoimmune diseases. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in a variety of applications, including Western blotting and immunohistochemistry.BTK is a key enzyme involved in B cell development and function, making it a promising target for therapeutic interventions in diseases like leukemia, lymphoma, and rheumatoid arthritis.
The BTK Rabbit Monoclonal Antibody binds specifically to BTK protein, allowing for accurate detection and quantification in various cell types and tissues.Researchers in immunology, oncology, and rheumatology will find this antibody indispensable for their studies on BTK signaling pathways and the development of targeted therapies for BTK-related diseases. With its high specificity and sensitivity, the BTK Rabbit Monoclonal Antibody is a reliable tool for advancing our understanding of BTK function and its implications in human health.
Product Name:
BTK Rabbit Monoclonal Antibody
SKU:
CAB19002
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 560-659 of human BTK (Q06187).
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
695
Clone Number:
ARC0485
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using BTK Rabbit mAb (CAB19002) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
