BTK Rabbit Polyclonal Antibody (CAB1576)
- SKU:
- CAB1576
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | BTK Rabbit Polyclonal Antibody |
SKU: | CAB1576 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTK (NP_000052.1). |
Sequence: | FLLT VHKL SYYE YDFE RGRR GSKK GSID VEKI TCVE TVVP EKNP PPER QIPR RGEE SSEM EQIS IIER FPYP FQVV YDEG PLYV FSPT EELR KRWI HQLK NVIR YNSD LVQK YHPC FWID GQYL CCSQ TAKN AMGC QILE NRNG SLKP GSSH RKTK KPLP PTPE EDQI LKKP LPPE PAAA PVST SELK KVVA LYDY MPMN ANDL QLRK GDE |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 |
Synonyms: | AT; ATK; BPK; XLA; IMD1; AGMX1; IGHD3; PSCTK1; BTK |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein. |
Calculated MW: | 76kDa |
Observed MW: | Refer to Figures |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 695 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |