The BTG4 Polyclonal Antibody (PAC041470) is a vital tool for researchers studying BTG4, a protein involved in cell cycle regulation and mRNA stability. This rabbit-derived antibody is highly specific for human samples and has been validated for use in Western blotting applications. It binds specifically to the BTG4 protein, allowing for accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.
BTG4 plays a crucial role in controlling cell proliferation and differentiation, making it a potential target for cancer therapy and other related diseases. Understanding the function of BTG4 is essential for developing innovative treatments that target this protein and its associated pathways. This antibody is a valuable tool for studying the role of BTG4 in various cellular processes and its potential implications in disease development and progression.
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO41470 at dilution of 1: 100.
Immunohistochemistry of paraffin-embedded human testis tissue using PACO41470 at dilution of 1:100.
Western Blot. Positive WB detected in: Mouse brain tissue. All lanes: BTG4 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 26, 25 kDa. Observed band size: 26 kDa.
Background:
Shows marked antiproliferative activity, being able to induce G(1) arrest.
Synonyms:
Protein BTG4 (BTG family member 4) (Protein PC3b), BTG4, PC3B
UniProt Protein Function:
BTG4: Shows marked antiproliferative activity, being able to induce G(1) arrest. Belongs to the BTG family.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 11q23Biological Process: cell cycle arrest; negative regulation of cell proliferation; neuron differentiation
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle. [provided by RefSeq, Jul 2008]
