BTBD2 Antibody (PACO31904)
- SKU:
- PACO31904
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
BTBD2 Antibody (PACO31904)
The BTBD2 Polyclonal Antibody (PAC031904) is a valuable tool for research involving the BTB/POZ domain-containing protein 2 (BTBD2), a crucial regulator of various cellular processes. This antibody, produced in rabbits, exhibits high specificity towards human samples and is validated for use in Western blot applications. By binding to the BTBD2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and disease research.
BTBD2, also known as BTB/POZ domain-containing protein 2, plays a significant role in cell cycle regulation and protein degradation mechanisms. Its involvement in these processes makes it a promising target for studies in cancer biology, neurodegenerative disorders, and developmental biology. Understanding the function of BTBD2 is crucial for unraveling its impact on cellular pathways and identifying potential therapeutic interventions to target diseases associated with its dysregulation.
| Antibody Name: | BTBD2 Antibody (PACO31904) |
| Antibody SKU: | PACO31904 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human BTB/POZ domain-containing protein 2 protein (321-525AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: BTBD2 antibody at 6µg/ml Lane 1: Hela whole cell lysate Lane 2: MDA-MB-231 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 56, 23 kDa Observed band size: 42 kDa . |
 | Immunofluorescent analysis of MCF-7 cells using PACO31904 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO31904 at dilution of 1:100. |
| Synonyms: | BTB/POZ domain-containing protein 2, BTBD2 |
| UniProt Protein Function: | Subunit structure: Interacts with topoisomerase 1 and with TRIM5 isoform Delta. Ref.1 Ref.7Subcellular location: Cytoplasm › P-body. Note: Cytoplasmic bodies. Ref.7Sequence similarities: Contains 1 BTB (POZ) domain.Sequence caution: The sequence AAC16070.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAB55143.1 differs from that shown. Reason: Erroneous initiation. |
| UniProt Protein Details: | |
| NCBI Summary: | The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BX70 |
| NCBI GenInfo Identifier: | 20127580 |
| NCBI Gene ID: | 55643 |
| NCBI Accession: | NP_060267.2 |
| UniProt Secondary Accession: | Q9BX70,O60418, O75248, Q4VBZ1, Q6IAC5, Q7Z5W0, Q96SX8 Q9NPS1, Q9NX81 |
| UniProt Related Accession: | Q9BX70 |
| Molecular Weight: | 48kD |
| NCBI Full Name: | BTB/POZ domain-containing protein 2 |
| NCBI Synonym Full Names: | BTB (POZ) domain containing 2 |
| NCBI Official Symbol: | BTBD2Â Â |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | BTB/POZ domain-containing protein 2 |
| UniProt Protein Name: | BTB/POZ domain-containing protein 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | BTB/POZ domain-containing protein |
| UniProt Gene Name: | BTBD2Â Â |
| UniProt Entry Name: | BTBD2_HUMAN |
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