The BTBD1 Polyclonal Antibody (CAB15161) is a valuable tool for researchers studying BTBD1, a protein known to play a role in various cellular processes including protein degradation and transcription regulation. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the BTBD1 protein, this antibody enables precise detection and analysis of BTBD1 levels in different cell types, making it ideal for studies in molecular biology and cancer research.
BTBD1 is a key player in cellular pathways regulating protein turnover and gene expression, highlighting its importance in maintaining cell homeostasis. Dysregulation of BTBD1 has been implicated in various diseases such as cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. Understanding the functions of BTBD1 is vital for uncovering its potential roles in disease development and progression, leading to innovative treatment strategies in the future.
Product Name:
BTBD1 Rabbit Polyclonal Antibody
SKU:
CAB15161
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human BTBD1 (NP_079514.1).
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
53339
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BTBD1 Rabbit pAb (CAB15161) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
