The BST2 Rabbit Monoclonal Antibody (CAB8839) is a high-quality antibody designed for research applications involving BST2, also known as bone marrow stromal antigen 2 or tetherin. This cell surface glycoprotein is involved in various cellular processes, including viral restriction, immune response modulation, and cell adhesion.This rabbit monoclonal antibody is highly specific and sensitive, making it an excellent tool for detecting and analyzing BST2 expression in a variety of cell types and tissues. It has been validated for use in Western blot, immunofluorescence, and immunohistochemistry applications, providing researchers with reliable results for their experiments.
BST2 is known to play a crucial role in immune response modulation, particularly in defense against viral infections. Its interaction with viral proteins and host cell proteins makes it a key player in antiviral immunity. Additionally, BST2 has been implicated in cancer progression and metastasis, making it a promising target for cancer research and therapy development.Overall, the BST2 Rabbit Monoclonal Antibody (CAB8839) is a valuable tool for studying the function of BST2 in various biological processes, offering researchers the opportunity to further understand its role in immune regulation, viral defense, and cancer biology.
Product Name:
BST2 Rabbit Monoclonal Antibody
SKU:
CAB8839
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human BST2 (Q10589).
Apical cell membrane, Cell membrane, Cytoplasm, GPI-anchor, Golgi apparatus, Late endosome, Lipid-anchor, Membrane raft, Single-pass type II membrane protein, trans-Golgi network.
Calculated MW:
20kDa
Observed MW:
35kDa
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.
Purification Method:
Affinity purification
Gene ID:
684
Clone Number:
ARC1321
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using BST2 Rabbit mAb (CAB8839) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
