The BST2 Polyclonal Antibody (CAB12315) is a valuable tool for researchers studying BST2, a cell surface protein known for its involvement in immune response and viral defense mechanisms. This antibody is produced in rabbits and has been shown to be highly specific for binding to human samples, making it an ideal choice for a wide range of research applications.BST2, also known as tetherin, is a key player in the innate immune response to viral infections, particularly in restricting the release of enveloped viruses from infected cells. Understanding the role of BST2 in viral pathogenesis and immune evasion is crucial for developing strategies to combat viral infections and enhance immune defenses.
This antibody has been validated for use in Western blot applications, allowing for the detection and analysis of BST2 protein levels in various cell types and experimental conditions. Its high reactivity and specificity make it a reliable tool for studying the function and regulation of BST2 in immunology, virology, and infectious disease research.Overall, the BST2 Polyclonal Antibody (CAB12315) offers a valuable resource for researchers investigating the complex interplay between BST2, immune responses, and viral infections, with potential implications for the development of novel therapeutic approaches in the fight against infectious diseases.
Product Name:
BST2 Rabbit Polyclonal Antibody
SKU:
CAB12315
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 49-161 of human BST2 (NP_004326.1).
Sequence:
NSEA CRDG LRAV MECR NVTH LLQQ ELTE AQKG FQDV EAQA ATCN HTVM ALMA SLDA EKAQ GQKK VEEL EGEI TTLN HKLQ DASA EVER LRRE NQVL SVRI ADKK YYPS SQDS S
Apical cell membrane, Cell membrane, Cytoplasm, GPI-anchor, Golgi apparatus, Late endosome, Lipid-anchor, Membrane raft, Single-pass type II membrane protein, trans-Golgi network.
Calculated MW:
20kDa
Observed MW:
35-40kDa
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis.
Purification Method:
Affinity purification
Gene ID:
684
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BST2 Rabbit pAb (CAB12315) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
