BSCL2 Rabbit Polyclonal Antibody (CAB14583)
- SKU:
- CAB14583
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | BSCL2 Rabbit Polyclonal Antibody |
SKU: | CAB14583 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 265-363 of human BSCL2 (NP_116056.3). |
Sequence: | RHRF SLQV NIRK RDNS RKEV QRRI SAHQ PGPE GQEE STPQ SDVT EDGE SPED PSGT EGQL SEEE KPDQ QPLS GEEE LEPE ASDG SGSW EDAA LLTE ANL |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HMN5; PELD; HMN5C; SPG17; GNG3LG; BSCL2 |
Positive Sample: | 293T,SH-SY5Y,Mouse brain,Mouse lung,Mouse testis,Rat brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Multi-pass membrane protein. |
Calculated MW: | 44kDa |
Observed MW: | 50kDa |
This gene encodes the multi-pass transmembrane protein protein seipin. This protein localizes to the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HNRNPUL2 (heterogeneous nuclear ribonucleoprotein U-like 2).
Purification Method: | Affinity purification |
Gene ID: | 26580 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |