The BRWD3 Polyclonal Antibody (PACO03772) is a valuable tool for researchers studying the BRWD3 protein, which is involved in chromatin remodeling and gene regulation. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blotting applications. By targeting the BRWD3 protein, this antibody allows for the detection and analysis of BRWD3 expression in various cell types, making it an essential resource for studies in epigenetics and cancer research.BRWD3 is a key player in chromatin dynamics and transcriptional regulation, making it essential for the proper functioning of cells.
Dysregulation of BRWD3 has been associated with various diseases, including cancer and developmental disorders. By investigating the role of BRWD3 in these conditions, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets.Overall, the BRWD3 Polyclonal Antibody (PACO03772) offers researchers a reliable tool for investigating the function of the BRWD3 protein in various biological processes, making it a valuable asset for studies in epigenetics, cancer biology, and beyond.
Antibody Name:
BRWD3 Antibody
Antibody SKU:
PACO03772
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human BRWD3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
BRWD3; Bromodomain and WD repeat-containing protein 3
UniProt Protein Function:
Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene are associated with a spectrum of cognitive disabilities and X-linked macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, Jul 2017]