BRWD1 Rabbit Polyclonal Antibody (CAB12656)
- SKU:
- CAB12656
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | BRWD1 Rabbit Polyclonal Antibody |
SKU: | CAB12656 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human BRWD1 (NP_001007247.1). |
Sequence: | MAEP SSAR RPVP LIES ELYF LIAR YLSA GPCR RAAQ VLVQ ELEQ YQLL PKRL DWEG NEHN RSYE ELVL SNKH VAPD HLLQ ICQR IGPM LDKE IPPS ISRV TSLL GAGR QSLL RTAK GTLI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 |
Synonyms: | N143; WDR9; WRD9; DCAF19; C21orf107; BRWD1 |
Positive Sample: | HeLa,Jurkat,SGC-7901,NIH/3T3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 263kDa |
Observed MW: | 263kDa |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.
Purification Method: | Affinity purification |
Gene ID: | 54014 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |