The BRSK2 Polyclonal Antibody (CAB17042) is a valuable tool for research into BRSK2, a serine/threonine kinase that plays a role in various cellular processes such as cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the BRSK2 protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for studies in cell biology and cancer research.
BRSK2, known for its involvement in cell signaling pathways, is a key player in regulating cell growth and survival. Its dysregulation has been linked to various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. Research into the role of BRSK2 is crucial for developing novel strategies to treat these conditions by targeting its activity in the affected cells.
Product Name:
BRSK2 Rabbit Polyclonal Antibody
SKU:
CAB17042
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human BRSK2 (NP_001243556.1).
centrosome, cytoplasm, endoplasmic reticulum, perinuclear region of cytoplasm
Calculated MW:
82kDa
Observed MW:
78-90kDa
Enables several functions, including ATP binding activity; ATPase binding activity; and protein kinase activity. Involved in several processes, including cellular protein metabolic process; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and regulation of insulin secretion involved in cellular response to glucose stimulus. Located in centrosome and endoplasmic reticulum.
Purification Method:
Affinity purification
Gene ID:
9024
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BRSK2 Rabbit pAb (CAB17042) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
