The BRSK1 Polyclonal Antibody (CAB17226) is a valuable tool for researchers studying the BRSK1 protein, which plays a crucial role in various cellular processes, including cell differentiation, proliferation, and survival. This antibody, produced in rabbits, is highly specific and reacts strongly with samples from various species, making it a versatile option for different experimental setups.BRSK1, a member of the AMP-activated protein kinase (AMPK) family, is involved in regulating multiple signaling pathways that impact cell growth and metabolism. By targeting the BRSK1 protein, researchers can gain insights into the mechanisms underlying these pathways and their implications for disease development and progression.
With its proven effectiveness in Western blot applications, the BRSK1 Polyclonal Antibody (CAB17226) enables reliable detection and analysis of the BRSK1 protein in different cell types and experimental conditions. Whether studying cellular signaling cascades, investigating disease mechanisms, or developing novel therapeutic strategies, this antibody is a valuable tool for advancing research in areas such as cancer biology, neurobiology, and metabolic disorders.
Product Name:
BRSK1 Rabbit Polyclonal Antibody
SKU:
CAB17226
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 310-510 of human BRSK1 (NP_115806.1).
Cell junction, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, synapse.
Calculated MW:
85kDa
Observed MW:
90kDa
Enables magnesium ion binding activity; protein serine/threonine kinase activity; and tau-protein kinase activity. Involved in mitotic G2 DNA damage checkpoint signaling and protein phosphorylation. Acts upstream of or within G2/M transition of mitotic cell cycle; peptidyl-serine phosphorylation; and response to UV. Located in cell junction; cytoplasm; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
84446
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Raji cells, using BRSK1 Rabbit pAb (CAB17226) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
