The BRS3 Polyclonal Antibody (PACO06300) is a specialized tool for researchers studying the BRS3 protein, a G-protein coupled receptor involved in various physiological processes, including metabolism and energy regulation. This antibody, produced in rabbits, shows high specificity for human samples and is optimized for Western blot applications. By targeting the BRS3 protein, researchers can accurately detect and analyze its expression in different cell types, making it an essential tool for studies in metabolic disorders and obesity research.BRS3, or Bombesin receptor subtype 3, plays a crucial role in regulating energy balance and appetite, making it a promising target for therapeutic interventions in obesity and related metabolic conditions.
By understanding the function and regulation of BRS3, researchers can develop novel treatments that target this receptor to modulate metabolic pathways and improve metabolic health.Overall, the BRS3 Polyclonal Antibody is a valuable tool for researchers investigating the role of BRS3 in metabolic disorders, and its high reactivity and specificity make it a reliable choice for Western blot analysis in these studies.
Antibody Name:
BRS3 Antibody (PACO06300)
Antibody SKU:
PACO06300
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
ELISA:1:40000, WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human BRS-3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western Blot analysis of various cells using BRS-3 Polyclonal Antibody.
Western Blot analysis of HuvEc cells using BRS-3 Polyclonal Antibody.
Synonyms:
BRS3; Bombesin receptor subtype-3; BRS-3
UniProt Protein Function:
BRS3: Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integralChromosomal Location of Human Ortholog: Xq26.3Cellular Component: neuron projection; cell soma; integral to membrane; plasma membraneMolecular Function: bombesin receptor activityBiological Process: regulation of blood pressure; bombesin receptor signaling pathway; glucose metabolic process; adult feeding behavior
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a G protein-coupled membrane receptor that binds bombesin-like peptides. This binding results in activation of a phosphatidylinositol-calcium second messenger system, with physiological effects including regulation of metabolic rate, glucose metabolism, and hypertension. [provided by RefSeq, Sep 2011]
