The BRPF1 Polyclonal Antibody (CAB17012) is a valuable tool for researchers studying BRPF1, a key component of the MOZ/MORF complex involved in histone acetylation and gene regulation. This antibody, generated in rabbits, demonstrates high specificity and sensitivity when detecting BRPF1 in human samples, making it ideal for use in Western blot applications.BRPF1 is essential for chromatin remodeling and transcriptional regulation, playing a vital role in cellular processes such as differentiation and development.
Dysregulation of BRPF1 has been linked to various diseases, including cancer and neurodevelopmental disorders, making it an attractive target for therapeutic intervention.By using the BRPF1 Polyclonal Antibody, researchers can gain valuable insights into the function of BRPF1 in normal cellular processes and disease states. Its ability to specifically detect BRPF1 in various cell types makes it an invaluable tool for investigations in molecular biology, epigenetics, and cancer research.
Product Name:
BRPF1 Rabbit Polyclonal Antibody
SKU:
CAB17012
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human BRPF1 (NP_001003694).
This gene encodes a bromodomain, PHD finger and chromo/Tudor-related Pro-Trp-Trp-Pro (PWWP) domain containing protein. The encoded protein is a component of the MOZ/MORF histone acetyltransferase complexes which function as a transcriptional regulators. This protein binds to the catalytic MYST domains of the MOZ and MORF proteins and may play a role in stimulating acetyltransferase and transcriptional activity of the complex. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using BRPF1 Rabbit pAb (CAB17012) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
