The BRINP2 Monoclonal Antibody (PAC040758) is a vital tool for researchers studying BRINP2, a protein involved in brain development and potentially linked to neurological disorders. This antibody, developed through mouse hybridoma technology, specifically targets BRINP2 in human samples and is validated for use in immunohistochemistry applications.BRINP2, also known as BMP/retinoic acid-inducible neural-specific protein 2, is believed to play a key role in neurogenesis and neuronal differentiation in the brain. Its expression patterns suggest involvement in processes like synaptic plasticity and memory formation.
Research on BRINP2 can provide insights into neurological conditions such as Alzheimer's disease, epilepsy, and Parkinson's disease.By utilizing the BRINP2 Monoclonal Antibody, scientists can accurately detect and study the distribution of BRINP2 in neural tissues, paving the way for a better understanding of its function and potential therapeutic implications. This antibody is a valuable tool for advancing research in neuroscience and neurological disorders.
Antibody Name:
BRINP2 Antibody (PACO40758)
Antibody SKU:
PACO40758
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human BMP/retinoic acid, inducible neural-specific protein 2 protein (34-300AA)
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO40758 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO40758 at dilution of 1:100.
Background:
Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition.
Synonyms:
BMP/retinoic acid, inducible neural-specific protein 2 (DBCCR1-like protein 2), BRINP2, DBCCR1L2 FAM5B KIAA1747
UniProt Protein Function:
FAM5B: Belongs to the FAM5 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1q24Cellular Component: cell soma; dendrite; endoplasmic reticulumBiological Process: negative regulation of mitotic cell cycle; positive regulation of neuron differentiation