BRE Rabbit Polyclonal Antibody (CAB15122)
- SKU:
- CAB15122
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | BRE Rabbit Polyclonal Antibody |
SKU: | CAB15122 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 51-229 of human BRE (NP_954661.1). |
Sequence: | PNCD RFKL HIPY AGET LKWD IIFN AQYP ELPP DFIF GEDA EFLP DPSA LQNL ASWN PSNP ECLL LVVK ELVQ QYHQ FQCS RLRE SSRL MFEY QTLL EEPQ YGEN MEIY AGKK NNWT GEFS ARFL LKLP VDFS NIPT YLLK DVNE DPGE DVAL LSVS FEDT EATQ VYPK LYLS PRIE HAL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | BRE; BRCC4; BRCC45 |
Positive Sample: | HeLa,HT-29,mouse brain,mouse heart,rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
Purification Method: | Affinity purification |
Gene ID: | 9577 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |