The BRD7 Polyclonal Antibody is a valuable tool for researchers studying the BRD7 protein, a key player in regulating gene expression and cell growth. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the BRD7 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component in studies related to cancer and epigenetics.BRD7, also known as Bromodomain-containing protein 7, is involved in controlling gene expression by influencing chromatin structure and transcriptional regulation.
Dysregulation of BRD7 has been linked to various cancers and other diseases, highlighting its importance as a potential therapeutic target. Research into the function of BRD7 is crucial for developing treatments that target the underlying molecular mechanisms of these conditions.In conclusion, the BRD7 Polyclonal Antibody is a valuable tool for researchers interested in understanding the role of BRD7 in health and disease. Its high specificity and reliability make it an ideal choice for studies aiming to uncover the molecular pathways regulated by BRD7 and its potential as a target for therapeutic intervention.
Product Name:
BRD7 Polyclonal Antibody
SKU:
CAB23265
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human BRD7. (NP_037395.2).
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29117
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using BRD7 Rabbit pAb (CAB23265) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
