The BRD7 Polyclonal Antibody (CAB2308) is specifically designed for research involving BRD7, a bromodomain-containing protein that plays a key role in regulating gene expression and cell growth. This antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. It binds to the BRD7 protein, allowing for detection and analysis in various cell types, making it ideal for studies in cancer research and epigenetics.BRD7 is a crucial factor in controlling cell proliferation and differentiation, making it a potential target for cancer therapy and other diseases related to abnormal cell growth.
Research into BRD7 is essential for understanding its function in gene regulation and its potential role in disease development. The BRD7 Polyclonal Antibody provides a valuable tool for investigating the mechanisms by which BRD7 influences cellular processes, offering insights that may lead to the development of novel therapeutic approaches.
Product Name:
[KO Validated] BRD7 Rabbit Polyclonal Antibody
SKU:
CAB2308
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human BRD7 (NP_037395.2).
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29117
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] BRD7 Rabbit pAb (CAB2308) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
