BRD2 Rabbit Polyclonal Antibody (CAB18229)
- SKU:
- CAB18229
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | BRD2 Rabbit Polyclonal Antibody |
SKU: | CAB18229 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human BRD2 (NP_005095.1). |
Sequence: | MLQN VTPH NKLP GEGN AGLL GLGP EAAA PGKR IRKP SLLY EGFE SPTM ASVP ALQL TPAN PPPP EVSN PKKP GRVT NQLQ YLHK VVMK ALWK HQFA WPFR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FSH; NAT; RNF3; FSRG1; RING3; FSHRG1; D6S113E; O27.1.1; BRD2-IT1; BRD2 |
Positive Sample: | HeLa,PC-3 |
Cellular Localization: | Nucleus. |
Calculated MW: | 88kDa |
Observed MW: | 115kDa |
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6046 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |