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BRCC3 Monoclonal Antibody [PAT3B1AT] (CPAB0167)

SKU:
CPAB0167
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT3B1AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

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BRCC3 Monoclonal Antibody [PAT3B1AT] (CPAB0167)

The BRCC3 Polyclonal Antibody (CPAB0167) is an essential tool for researchers studying BRCC3, a protein involved in DNA repair and regulation of cell cycle progression. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the BRCC3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in DNA repair mechanisms, cancer research, and cell biology.

BRCC3, also known as BRCC36, is a member of the BRCA1-A complex and plays a crucial role in maintaining genomic stability by participating in DNA damage response pathways. Dysregulation of BRCC3 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in cellular homeostasis and disease development. By investigating the function of BRCC3, researchers can gain valuable insights into potential therapeutic targets for treating these conditions.

Product Name:BRCC3 Antibody
Product Sku:CPAB0167
Size:5μg
Host Species:Mouse
Immunogen:Anti-human BRCC3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BRCC3 amino acids 1-316 purified from Ecoli.
Clone:PAT3B1AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:BRCC3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:BRCC3 is a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. BRCC3 is also thought to be involved in the cellular response to ionizing radiation and progression through the G2/M checkpoint.
Synonyms:Lys-63-specific deubiquitinase BRCC36, BRCA1-A complex subunit BRCC36, BRISC complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCC3, BRCC36, C6.1A, CXorf53, C6.1A, RP11-143H17.2.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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