The BRCA2 Polyclonal Antibody (PAC061326) is a valuable tool for research focused on the BRCA2 protein, which is known for its role in DNA repair and maintenance of genomic stability. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blotting.BRCA2 is a critical tumor suppressor gene that helps prevent the development of breast, ovarian, and other cancers. Mutations in BRCA2 have been linked to an increased risk of hereditary breast and ovarian cancer. Understanding the function and regulation of BRCA2 is essential for developing targeted therapies for individuals with BRCA2 mutations and for advancing cancer treatment strategies.
Researchers studying DNA repair mechanisms, genomic stability, and cancer biology will find the BRCA2 Polyclonal Antibody to be a reliable tool for their experiments. Its high specificity and sensitivity make it suitable for detecting and analyzing BRCA2 protein levels in various cell types, providing valuable insights into the molecular mechanisms underlying cancer development and progression.
Antibody Name:
brca2 Antibody (PACO61326)
Antibody SKU:
PACO61326
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Zebrafish
Immunogen:
Recombinant Zebrafish Breast cancer 2, early onset protein (2737-2874AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: brca2 antibody at 1.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45 kDa. Observed band size: 52 kDa.