BPIFB3 Antibody (PACO18163)
- SKU:
- PACO18163
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
BPIFB3 Antibody (PACO18163)
The BPIFB3 Polyclonal Antibody (PAC018163) is a valuable tool for researchers studying BPIFB3, a secretory protein involved in innate immunity and airway defense. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in Western blot applications. By binding to the BPIFB3 protein, this antibody enables the detection and analysis of BPIFB3 levels in various cell types, making it an ideal choice for studies in respiratory biology and infectious disease research.
BPIFB3, also known as SPLUNC3, plays a crucial role in maintaining mucosal homeostasis and defending against respiratory infections. Its involvement in host defense mechanisms makes it a promising target for investigating conditions such as chronic obstructive pulmonary disease (COPD), asthma, and cystic fibrosis. By elucidating the function of BPIFB3, researchers can gain insights that may lead to the development of novel therapeutics for these respiratory disorders.
Antibody Name: | BPIFB3 Antibody (PACO18163) |
Antibody SKU: | PACO18163 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human BPIFB3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18163(BPIFB3 Antibody) at dilution 1/120, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human lung cancer tissue, Primary antibody: PACO18163(BPIFB3 Antibody) at dilution 1/1600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18163(BPIFB3 Antibody) at dilution 1/120, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | BPI fold-containing family B member 3 may have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received. |
Synonyms: | BPI fold containing family B, member 3 |
UniProt Protein Function: | BPIFB3: May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 20q11.21 Cellular Component: cytoplasm; extracellular region Molecular Function:lipid binding Biological Process: innate immune response |
UniProt Code: | P59826 |
NCBI GenInfo Identifier: | 73620973 |
NCBI Gene ID: | |
NCBI Accession: | P59826.2 |
Molecular Weight: | 50kDa |
NCBI Full Name: | BPI fold-containing family B member 3 |
UniProt Protein Name: | BPI fold-containing family B member 3 |
UniProt Synonym Protein Names: | Ligand-binding protein RYA3; Long palate, lung and nasal epithelium carcinoma-associated protein 3 |
Protein Family: | BPI fold-containing family |
UniProt Gene Name: | BPIFB3 |
UniProt Entry Name: | BPIB3_HUMAN |