BPIFB1 Antibody (PACO18159)
- SKU:
- PACO18159
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
BPIFB1 Antibody (PACO18159)
The BPIFB1 Monoclonal Antibody (PAC018159) is a cutting-edge tool for researchers studying BPIFB1, a key protein involved in innate immunity and respiratory health. This antibody, generated from mouse clones, exhibits high specificity and sensitivity for BPIFB1 detection in human samples, making it a reliable choice for Western blot applications.BPIFB1, also known as BPI fold-containing family B member 1, plays a crucial role in the defense against respiratory pathogens and maintaining the integrity of airway epithelial cells. Dysregulation of BPIFB1 has been associated with various respiratory diseases, including chronic obstructive pulmonary disease (COPD) and bronchitis.
By targeting BPIFB1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic approaches.The BPIFB1 Monoclonal Antibody is an invaluable tool for investigating the function and regulation of BPIFB1 in the context of respiratory health and disease. Its ability to specifically bind to BPIFB1 provides researchers with a powerful means of studying this important protein in various experimental settings, advancing our understanding of respiratory biology and paving the way for potential therapeutic interventions.
| Antibody Name: | BPIFB1 Antibody (PACO18159) |
| Antibody SKU: | PACO18159 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human BPIFB1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 50 μg, Lane 1-2: Human tongue tissue, Human laryngocarcinoma tissue, Primary antibody: PACO18159(BPIFB1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO18159(BPIFB1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. |
| Synonyms: | BPI fold containing family B, member 1 |
| UniProt Protein Function: | LPLUNC1: May play a role in innate immunity in mouth, nose and lungs. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 20q11.21 Cellular Component: extracellular space; extracellular region Molecular Function:lipid binding Biological Process: innate immune response in mucosa; negative regulation of toll-like receptor 4 signaling pathway |
| NCBI Summary: | The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TDL5 |
| NCBI GenInfo Identifier: | 34395685 |
| NCBI Gene ID: | 92747 |
| NCBI Accession: | Q8TDL5.1 |
| UniProt Secondary Accession: | Q8TDL5,Q5QP43, Q6UWY1, Q6ZRU7, Q96HK6, Q9BQP8, Q9BWZ6 Q9H4V6, A8K2H8, |
| UniProt Related Accession: | Q8TDL5 |
| Molecular Weight: | 484 |
| NCBI Full Name: | BPI fold-containing family B member 1 |
| NCBI Synonym Full Names: | BPI fold containing family B, member 1 |
| NCBI Official Symbol: | BPIFB1Â Â |
| NCBI Official Synonym Symbols: | LPLUNC1; C20orf114Â Â |
| NCBI Protein Information: | BPI fold-containing family B member 1; VEMSGP; von Ebner minor salivary gland protein; long palate, lung and nasal epithelium carcinoma associated 1; long palate, lung and nasal epithelium carcinoma-associated protein 1 |
| UniProt Protein Name: | BPI fold-containing family B member 1 |
| UniProt Synonym Protein Names: | Long palate, lung and nasal epithelium carcinoma-associated protein 1; Von Ebner minor salivary gland protein; VEMSGP |
| Protein Family: | BPI fold-containing family |
| UniProt Gene Name: | BPIFB1Â Â |
| UniProt Entry Name: | BPIB1_HUMAN |
Related Products
BPIFB1 Antibody (PACO18158)
SPEF2 Antibody (PACO64977)
C1QTNF9 Antibody (PACO64617)
POTEE Antibody (PACO64901)
ompF Antibody (PACO64865)
