BPIFB1 Antibody (PACO18158)
- SKU:
- PACO18158
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
BPIFB1 Antibody (PACO18158)
The BPIFB1 Polyclonal Antibody (PAC018158) is a crucial tool for researchers studying BPIFB1, a protein associated with respiratory health and immune response. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot assays. By binding to the BPIFB1 protein, this antibody allows for the accurate detection and analysis of BPIFB1 expression in various cell types, making it an invaluable tool for studies in respiratory diseases and immune system function.BPIFB1, also known as BPI fold-containing family B member 1, is involved in maintaining respiratory epithelial barrier integrity and promoting immune defense in the airways.
Its role in protecting against respiratory infections and inflammation makes it a promising target for research into respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. Understanding the function of BPIFB1 can provide insight into potential therapeutic strategies for managing these conditions and improving respiratory health.
| Antibody Name: | BPIFB1 Antibody (PACO18158) |
| Antibody SKU: | PACO18158 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human BPIFB1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18158(BPIFB1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18158(BPIFB1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. |
| Synonyms: | BPI fold containing family B, member 1 |
| UniProt Protein Function: | LPLUNC1: May play a role in innate immunity in mouth, nose and lungs. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 20q11.21 Cellular Component: extracellular space; extracellular region Molecular Function:lipid binding Biological Process: innate immune response in mucosa; negative regulation of toll-like receptor 4 signaling pathway |
| NCBI Summary: | The protein encoded by this gene may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TDL5 |
| NCBI GenInfo Identifier: | 34395685 |
| NCBI Gene ID: | 92747 |
| NCBI Accession: | Q8TDL5.1 |
| UniProt Secondary Accession: | Q8TDL5,Q5QP43, Q6UWY1, Q6ZRU7, Q96HK6, Q9BQP8, Q9BWZ6 Q9H4V6, A8K2H8, |
| UniProt Related Accession: | Q8TDL5 |
| Molecular Weight: | 484 |
| NCBI Full Name: | BPI fold-containing family B member 1 |
| NCBI Synonym Full Names: | BPI fold containing family B, member 1 |
| NCBI Official Symbol: | BPIFB1Â Â |
| NCBI Official Synonym Symbols: | LPLUNC1; C20orf114Â Â |
| NCBI Protein Information: | BPI fold-containing family B member 1; VEMSGP; von Ebner minor salivary gland protein; long palate, lung and nasal epithelium carcinoma associated 1; long palate, lung and nasal epithelium carcinoma-associated protein 1 |
| UniProt Protein Name: | BPI fold-containing family B member 1 |
| UniProt Synonym Protein Names: | Long palate, lung and nasal epithelium carcinoma-associated protein 1; Von Ebner minor salivary gland protein; VEMSGP |
| Protein Family: | BPI fold-containing family |
| UniProt Gene Name: | BPIFB1Â Â |
| UniProt Entry Name: | BPIB1_HUMAN |
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