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BPGM Monoclonal Antibody [PA2E11AT] (CPAB0254)

SKU:
CPAB0254
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PA2E11AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

BPGM Monoclonal Antibody [PA2E11AT] (CPAB0254)

The BPGM Polyclonal Antibody (CPAB0254) is a valuable tool for researchers studying the enzyme BPGM, which plays a crucial role in the glycolysis pathway. This antibody is produced in rabbits and is highly reactive with human samples, making it ideal for Western blot applications. By binding to the BPGM protein, this antibody allows for the detection and analysis of BPGM in various cell types, facilitating research in biochemistry and metabolic pathways.BPGM, also known as bisphosphoglycerate mutase, is involved in the regulation of red blood cell metabolism and oxygen transport. Its role in glycolysis makes it a key target for studies on metabolic diseases, such as diabetes and cancer, as well as conditions related to oxygen transport and energy production.

Understanding the function of BPGM is essential for developing targeted therapies and treatments for these complex diseases.Overall, the BPGM Polyclonal Antibody (CPAB0254) offers researchers a reliable and specific tool for investigating the role of BPGM in cellular metabolism and disease pathology. Its high reactivity and validation in Western blot applications make it a valuable asset for scientists conducting research in the fields of biochemistry, metabolism, and disease.

Product Name:BPGM Antibody
Product Sku:CPAB0254
Size:5μg
Host Species:Mouse
Immunogen:Anti-human BPGM mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human BPGM amino acids 1-259 purified from Ecoli.
Clone:PA2E11AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:BPGM antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:BPGM is found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. PGM deficiency increases the oxygen affinity of cells. BPGM is a multifunctional enzyme that catalyzes 2,3-DPG synthesis through its synthetase activity, and 2,3-DPG degradation using its phosphatase activity. BPGM has phosphoglycerate phosphomutase activity. Mutations in BPGM cause hemolytic anemia. BPGM catalyzes the reaction of EC 5.4.2.1 (mutase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
Synonyms:Bisphosphoglycerate mutase, EC 5.4.2.4, BPGM, 2,3-bisphosphoglycerate mutase erythrocyte, 2,3-bisphosphoglycerate synthase, BPG-dependent PGAM.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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