The BOTD Polyclonal Antibody (PACO34270) is a powerful tool for researchers studying BOTD, a key protein involved in cellular function and immune signaling pathways. This antibody, raised in rabbits, is highly specific to human samples and has been validated for Western blotting applications. By binding to the BOTD protein, researchers can easily detect and analyze its expression in various cell types, making it a valuable asset for studies in immunology and cancer research.BOTD, also known as a crucial immune regulator, plays a vital role in modulating immune responses and maintaining immune homeostasis.
Its involvement in these processes makes it an attractive target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By delving into the functions of the BOTD protein, researchers can gain insights crucial for the development of novel therapies that aim to modulate immune responses and combat these diseases effectively.
Antibody Name:
botD Antibody (PACO34270)
Antibody SKU:
PACO34270
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Clostridium botulinum
Immunogen:
Recombinant Clostridium botulinum Botulinum neurotoxin type D protein (1-442AA)
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '60-Lys- |-Leu-61' bond of synaptobrevins-1 and -2.
Synonyms:
Botulinum neurotoxin type D (BoNT/D) (EC 3.4.24.69) (Bontoxilysin-D) [Cleaved into: Botulinum neurotoxin D light chain; Botulinum neurotoxin D heavy chain], botD
UniProt Protein Function:
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '60-Lys-|-Leu-61' bond of synaptobrevins-1 and -2.
