The BOTB Antibody (PACO34130) is a highly specific polyclonal antibody designed for research involving the CD300A protein. CD300A is a cell surface molecule known for its role in immune regulation, specifically inhibiting immune responses. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications.The BOTB Antibody binds specifically to the CD300A protein, enabling researchers to detect and analyze its expression in various cell types. This makes it an ideal tool for studies in immunology and cancer research, where understanding the role of CD300A is crucial.
CD300A, also known as an immune inhibitory receptor, plays a critical role in immune homeostasis by regulating inflammation and inhibiting allergic reactions. Its significance in immune response modulation makes it a valuable target for research into diseases like cancer, autoimmune disorders, and chronic inflammatory conditions. By studying the activity of CD300A using the BOTB Antibody, researchers can gain insights that may lead to the development of novel therapies that modulate immune function in these disease contexts.
Antibody Name:
botB Antibody (PACO34130)
Antibody SKU:
PACO34130
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Clostridium botulinum
Immunogen:
Recombinant Clostridium botulinum Botulinum neurotoxin type B protein (1-427AA)
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '76-Gln- |-Phe-77' bond of synaptobrevin-2.
Synonyms:
Botulinum neurotoxin type B (BoNT/B) (EC 3.4.24.69) (Bontoxilysin-B) [Cleaved into: Botulinum neurotoxin B light chain; Botulinum neurotoxin B heavy chain], botB
UniProt Protein Function:
Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
