The BORA Polyclonal Antibody (CAB13847) is a valuable tool for researchers studying BORA, a protein involved in cell cycle regulation and cell division. This antibody, produced in rabbits, is highly specific to human BORA protein and has been validated for use in Western blot applications. By binding to BORA, this antibody allows for the detection and analysis of the protein in various cell types, making it an essential tool for studies in cell biology and cancer research.BORA is known to play a critical role in the regulation of mitotic entry and the progression of cell division.
Dysregulation of BORA has been linked to abnormal cell growth and tumorigenesis, making it a promising target for cancer therapy research. Understanding the function of BORA is essential for uncovering its potential as a therapeutic target for cancer treatment and other cell cycle-related disorders.Overall, the BORA Polyclonal Antibody (CAB13847) offers researchers a reliable tool for investigating the role of BORA in cell cycle regulation and cancer development, providing valuable insights that could lead to the development of new therapeutic strategies.
Product Name:
BORA Rabbit Polyclonal Antibody
SKU:
CAB13847
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-619 of human BORA (NP_079084.3).
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).
Purification Method:
Affinity purification
Gene ID:
79866
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using BORA Rabbit pAb (CAB13847) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 40s.
