The BNIPL Antibody (PAC08033) is a polyclonal antibody specifically designed for research involving BNIPL, a protein involved in regulating apoptosis and autophagy. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.BNIPL, also known as BCL2/adenovirus E1B 19kD-interacting protein 3-like protein, plays a crucial role in cell death pathways and is associated with various diseases, including cancer and neurodegenerative disorders.
By targeting BNIPL with this antibody, researchers can gain insights into its function and potential therapeutic applications in these areas.With its high specificity and sensitivity, the BNIPL Antibody (PAC08033) is a valuable tool for studying the role of BNIPL in cellular processes and disease development. Whether investigating apoptosis mechanisms or exploring potential treatment strategies, this antibody is an essential component for any research project focused on understanding the molecular pathways involving BNIPL.
BCL2/adenovirus E1B 19kD interacting protein like;BNIPL;BNIP-S;BNIPL-1;BNIPL-2;BNIPL1;BNIPL2;PP753 ;
UniProt Protein Function:
BNIPL: May be a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 1q21.3Cellular Component: nucleus; cytosolMolecular Function: identical protein binding; protein bindingBiological Process: negative regulation of cell proliferation; apoptosis; regulation of growth rate
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
